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Percocet (Oxycodone and Acetaminophen): Uses, Safety Information & Medical Guidance
What Is Percocet?
Percocet is a prescription medication that combines oxycodone, an opioid pain reliever, and acetaminophen, a non-opioid analgesic. It is used to treat moderate to severe pain when an opioid medication is considered medically appropriate. Because Percocet contains an opioid, it carries significant risks of misuse, dependence, addiction, overdose, and serious side effects, and it should only be used under the supervision of a licensed healthcare professional.

Medical Uses
A healthcare provider may prescribe Percocet for:

Moderate to severe acute pain
Pain following surgery or injury
Short-term pain management when non-opioid medications alone are not sufficient
The dosage and duration of treatment are individualized based on the patient’s condition, medical history, previous opioid use, and response to therapy.

How Percocet Works
Percocet contains two active ingredients that work together:

Oxycodone binds to opioid receptors in the brain and spinal cord, reducing the perception of pain.
Acetaminophen helps relieve pain and may enhance the overall pain-relieving effects of oxycodone.
Together, these ingredients provide effective pain relief when used exactly as prescribed.

Important Safety Information
Percocet should only be taken exactly as directed by a healthcare professional.

Possible side effects include:

Drowsiness
Dizziness
Nausea or vomiting
Constipation
Dry mouth
Sleepiness
Serious risks include slowed or stopped breathing, overdose, physical dependence, addiction, misuse, and liver damage if excessive acetaminophen is taken.

Do not consume alcohol or combine Percocet with benzodiazepines or other medications that depress the central nervous system unless specifically instructed by your healthcare provider.

Responsible Use
Before taking Percocet, tell your healthcare provider if you have:

Liver or kidney disease
Asthma or other breathing disorders
A history of substance use disorder
Head injury or seizure disorders
Pregnancy or breastfeeding
Any prescription medications, over-the-counter medicines, vitamins, or herbal supplements you are taking
Never increase your dose, take the medication more frequently than prescribed, or share it with another person.

Storage
Store Percocet securely in its original container at room temperature, away from heat, moisture, and direct sunlight. Keep it out of the reach of children and anyone for whom it was not prescribed. Dispose of unused medication through an authorized medication take-back program when available.

Final Note
Percocet can be an effective treatment for moderate to severe pain when used appropriately under medical supervision. Always follow your healthcare provider’s instructions, attend recommended follow-up appointments, and obtain prescription medications through licensed healthcare providers and authorized pharmacies.